Try to schedule your winery visits so that each day you focus on one small area so you don't spend a lot of time backtracking. Also while the wineries on Hwy 29 are pretty easy / fast to get to, if you go into the mountains like for Pride it takes a while. Also if you want to maximize number of wineries, then try to minimize on appointment-only places as it puts you in a time-crunch / schedule maintenance which can be a hassle to manage.
I'm a big fan of Duckhorn/Paraduxx. I'd just do Pride & skip Spring Mountain, but honestly if it's your first Napa visit and you're short of time, I'm not sure I'd go to either as the appointment-only is a hassle. Artesa is pretty but the wines aren't my favorite. If you're somewhat knowledgeable about wine, I really like the blend classes (I've tried the ones at Paraduxx & Franciscan) -- downside is that they're appt only and take quite a bit of time (~2 hours), but it's really cool to have such a hands-on class and learn about wine blending.
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